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Tag Archives | Biotransformation

Biotransformation of Toxicants in Animals | Toxicology

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A xenobiotic (toxicant) may be absorbed into an animal via different routes. After absorption it is distributed to different parts of the body and, finally, is available for excretion. Many xenobiotics are known to undergo biotransformation while in the organs and tissues. Biotransformation is also termed metabolic transformation. Definition of Biotransformation: Biotrans­formation may be defined […]

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    Phases of Biotransformation: 2 Phases | Toxicants | Toxicology

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    The following points highlight the two main phases of biotransformation of toxicants. The phases are: 1. Phase I Reactions 2. Phase II Reactions. 1. Phase I Reactions: There are three types of Phase I reactions: i. Oxidation. ii. Reduction. iii. Hydrolysis. 1. Oxidation: The biotransformation of great variety of xenobiotic compounds involves oxidation process. The […]

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